abstract：:The present study investigates the role of melanotrope proopiomelanocortin-derived peptide in the interrenal stress response to different stressors in male gilthead sea bream, Sparus aurata. Plasma cortisol and acetyl salmon endorphin (acetyl s-EP), as well as pituitary acetyl s-EP contents, were measured during two s...

journal_title：Neuroendocrinology

authors： Mosconi G,Gallinelli A,Polzonetti-Magni AM,Facchinetti F

更新日期：1998-08-01 00:00:00

abstract：:In human African trypanosomiasis (sleeping sickness), sleep and wake episodes are sporadically distributed throughout the day and the night. Plasma melatonin, sleep-wakefulness and rectal temperature rhythms were studied in 9 Congolese patients suffering from sleeping sickness compared to 6 healthy controls submitted ...

journal_title：Neuroendocrinology

authors： Claustrat B,Buguet A,Geoffriau M,Bogui P,Mouanga G,Stanghellini A,Dumas M

更新日期：1998-07-01 00:00:00

abstract：:Adrenocorticotropic hormone (ACTH) is the major regulator of adrenocortical steroidogenesis in mammals. By comparing the sensitivity to ACTH of isolated adrenocortical cells from two sources of the same strain (Sprague-Dawley, SD) of outbred rats, we have identified a source of rat with low sensitivity to ACTH in vitr...

journal_title：Neuroendocrinology

authors： Matthys L,Castello R,Zilz A,Widmaier EP

更新日期：1998-06-01 00:00:00

abstract：:The obese gene (OB) product, leptin, has been shown to exert control on metabolic processes such as food intake and body weight homeostasis, possibly through a neuropeptide Y (NPY) neurotransmission. More recently, leptin has been shown to control several neuroendocrine axes, modulating pituitary hormone secretions in...

journal_title：Neuroendocrinology

authors： Vuagnat BA,Pierroz DD,Lalaoui M,Englaro P,Pralong FP,Blum WF,Aubert ML

更新日期：1998-05-01 00:00:00

abstract：:The present study provides evidence of a novel neuronal pathway for the control of GnRH secretion involving bradykinin neurons. Bradykinin neurons were shown by immunohistochemistry to be densely localized in several regions of the brain including the cortex, hippocampus and supraoptic nucleus, as well as two regions ...

journal_title：Neuroendocrinology

authors： Shi B,Mahesh VB,Bhat GK,Ping L,Brann DW

更新日期：1998-04-01 00:00:00

abstract：:Pulsatile gonadotropin-releasing hormone (GnRH) release from the median eminence is critical for the appropriate function of the pituitary gonadotropes and for the generation of a preovulatory gonadotropin surge. The mechanisms by which many GnRH axon terminals are synchronized to release GnRH in a coordinated fashion...

journal_title：Neuroendocrinology

authors： Hosny S,Jennes L

更新日期：1998-02-01 00:00:00

abstract：:Corticosteroids regulate gene expression through the activation of mineralocorticoid and glucocorticoid receptors. The hippocampus contains the highest density of mineralocorticoid and glucocorticoid receptors in the central nervous system. The modulation of neuron excitability by corticosteroids in hippocampal subfie...

journal_title：Neuroendocrinology

authors： Okuhara DY,Beck SG

更新日期：1998-01-01 00:00:00

abstract：:The effects of angiotensin II (AII) and natriuretic peptide (ANP), alone or in combination, on tuberoinfundibular dopaminergic (TIDA) neuronal activity and on serum PRL levels were examined in this study. The TIDA neuronal activity was determined by measuring 3,4-dihydroxyphenylacetic acid (DOPAC) concentration in the...

journal_title：Neuroendocrinology

authors： Yen SH,Pan JT

更新日期：1997-11-01 00:00:00

abstract：:It is not known where melatonin acts to influence the neuroendocrine axis of seasonally breeding mammals. However, since the pars tuberalis (PT) contains the highest density of melatonin receptors, this adenohypophyseal subdivision is a potential target. Gonadotropes are the only immunocytochemically detectable adenoh...

journal_title：Neuroendocrinology

authors： Skinner DC,Robinson JE

更新日期：1997-10-01 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:In addition to its traditional role as a circulating vasoactive peptide, vasopressin (VP) has been shown to play significant roles in central cardiovascular processing. The recent description of VP receptors within the subfornical organ (SFO) has suggested this circumventricular organ (CVO) as a potential locus for fe...

journal_title：Neuroendocrinology

authors： Smith PM,Ferguson AV

更新日期：1997-08-01 00:00:00

abstract：:Recent work has demonstrated that the brain has the capacity to synthesize impressive amounts of the gases nitric oxide (NO) and carbon monoxide (CO). There is growing evidence that these gaseous molecules function as novel neural messengers in the brain. This article reviews the pertinent literature concerning the pu...

journal_title：Neuroendocrinology

authors： Brann DW,Bhat GK,Lamar CA,Mahesh VB

更新日期：1997-06-01 00:00:00

abstract：:We report the development of a radioimmunoassay for prepro-TRH(160-169) (PS4), a thyrotropin-releasing hormone (TRH) enhancing peptide, and its use in characterizing the effect of electroconvulsive seizures on the levels of this peptide in various brain regions of male Wistar rats. We found that electroconvulsive seiz...

journal_title：Neuroendocrinology

authors： Pekary AE,Sattin A,Lloyd RL

更新日期：1997-05-01 00:00:00

abstract：:Interactions between the hypothalamic-pituitary-adrenocortical (HPA) system and melatonin secretion have been demonstrated, but only the effects of melatonin on the activity of the HPA system have been studied in man. Alterations of melatonin secretion described as low-melatonin syndrome have been demonstrated in pati...

journal_title：Neuroendocrinology

authors： Kellner M,Yassouridis A,Manz B,Steiger A,Holsboer F,Wiedemann K

更新日期：1997-04-01 00:00:00

abstract：:Brain corticosteroid receptors, the type 1 mineralocorticoid receptor (MR) and the type 2 glucocorticoid receptor (GR), are involved in the regulation of neuroendocrine and behavioral responses during ongoing and stressful conditions. To further investigate the role of MR in these responses, we treated male Wistar rat...

journal_title：Neuroendocrinology

authors： Reul JM,Probst JC,Skutella T,Hirschmann M,Stec IS,Montkowski A,Landgraf R,Holsboer F

更新日期：1997-03-01 00:00:00

abstract：:Neuroendocrine mechanisms governing growth hormone (GH) secretion are sensitive to nutritional status since the normal pulsatile pattern of GH release is disrupted during conditions of food deprivation or malnutrition. A reasonable hypothesis for this occurrence is the alteration of somatostatin and GH-releasing hormo...

journal_title：Neuroendocrinology

authors： Brogan RS,Fife SK,Conley LK,Giustina A,Wehrenberg WB

更新日期：1997-02-01 00:00:00

abstract：:Oxytocin receptors are regulated during parturition and lactation. Gonadal steroids are thought to be key players in this regulation. It is not well documented how oxytocin receptor gene expression is regulated in the CNS. In this study we analyzed potential estrogen effects on the oxytocin receptor mRNA levels in som...

journal_title：Neuroendocrinology

authors： Quiñones-Jenab V,Jenab S,Ogawa S,Adan RA,Burbach JP,Pfaff DW

更新日期：1997-01-01 00:00:00

abstract：:Prolactin (PRL) secretion from the anterior pituitary is tonically controlled by the activity of the hypothalamic tuberoinfundibular dopaminergic (TIDA) system. Changes in TIDA activity have been associated with the decrease in basal PRL levels shown by hamsters exposed to a short-day photoperiod. Potential concurrent...

journal_title：Neuroendocrinology

authors： Badura LL

更新日期：1996-12-01 00:00:00

abstract：:The neuropeptide galanin (GAL) is widely distributed in the central and peripheral nervous systems where it often coexists with catecholamines and acetylcholine. Recently we have reported that human GAL (hGAL) in man depresses the release of norepinephrine (NE) and the responses to both assumption of upright posture a...

journal_title：Neuroendocrinology

authors： degli Uberti EC,Bondanelli M,Margutti A,Ambrosio MR,Valentini A,Campo M,Franceschetti P,Zatelli MC,Pansini R,Trasforini G

更新日期：1996-11-01 00:00:00

abstract：:In order to evaluate the possible participation of the hypothalamic excitatory and inhibitory amino acid neurotransmitter systems in the GnRH release response to GABAergic drugs, hypothalami (preoptic and mediobasal area) of immature (26 days of age) and adult male rats were perifused with GABA-A and -B agonists and a...

journal_title：Neuroendocrinology

authors： Feleder C,Jarry H,Leonhardt S,Wuttke W,Moguilevsky JA

更新日期：1996-10-01 00:00:00

abstract：:In the primate, arginine vasopressin (AVP) is known to activate the hypothalamo-pituitary-adrenal axis and to inhibit LH secretion. In the present study, we investigate the role of the endogenous opioid peptides and corticotropin-releasing hormone (CRH) in these processes. Adult ovariectomized rhesus monkeys bearing a...

journal_title：Neuroendocrinology

authors： Xiao E,Xia-Zhang L,Thornell D,Shalts E,Ferin M

更新日期：1996-09-01 00:00:00

abstract：:This study examines the neural lobe of the pituitary gland for the presence of receptors for pituitary adenylate cyclase-activating polypeptide (PACAP) and their possible involvement in the regulation of neurosecretion. The presence of PACAP receptors of type I was revealed in the neural lobe, as well as in anterior a...

journal_title：Neuroendocrinology

authors： Lutz-Bucher B,Monnier D,Koch B

更新日期：1996-08-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) receptors were characterized and their function investigated in mouse pituitary neurointermediate lobe explants. We show that mouse neurointermediate lobes can be maintained for up to 1 month in defined medium. After 8 days in culture, these explants are devoi...

journal_title：Neuroendocrinology

authors： René F,Monnier D,Gaiddon C,Félix JM,Loeffler JP

更新日期：1996-07-01 00:00:00

abstract：:The purpose of the present study was to evaluate the opioid receptor subtype mediating opioid modulation of growth hormone (GH) secretion during ontogeny. The mu-agonist morphine and the kappa agonist U50,488 caused a stimulation and inhibition of GH secretion, respectively, on postnatal day 10. Studies on postnatal d...

journal_title：Neuroendocrinology

authors： Eason MG,Francis RS,Kuhn CM

更新日期：1996-06-01 00:00:00

abstract：:The inhibitory effects of pituitary allografts on the prolactin (PRL)-secretory system are presumed to be consequences of the unabated release of PRL by the allografts. In the present studies we used pituitary allografts in the Golden Syrian hamster to address the following questions: (a) Do allografts of adult adenoh...

journal_title：Neuroendocrinology

authors： Campbell GT,Gore AC,Woller MJ,Blake CA

更新日期：1996-05-01 00:00:00

abstract：:Pit-1 expression has been reported to be cell-type-specific in the adult human pituitary and in human pituitary adenomas. In contrast, studies of rodent fetal adenohypophysial development as well as mature rodent glands have indicated that the pit-1 mRNA is ubiquitously expressed and the protein is under translational...

journal_title：Neuroendocrinology

authors： Puy LA,Asa SL

更新日期：1996-04-01 00:00:00

abstract：:The involvement of histaminergic transmission in the rapid and sustained plasma ACTH and corticosterone (CORT) responses induced in conscious rats by intra-arterial infusions of 25 micrograms.kg-1 Escherichia coli lipopolysaccharide (LPS) was investigated. LPS challenge produced a rapid and transient increase (+ 62%) ...

journal_title：Neuroendocrinology

authors： Givalois L,Siaud P,Mekaouche M,Ixart G,Malaval F,Assenmacher I,Barbanel G

更新日期：1996-03-01 00:00:00

abstract：:A double immunocytochemical procedure, with two different chromogens, was used to compare the respective distribution of estrogen receptor-immunoreactive cells and tyrosine hydroxylase-immunoreactive neurons on the same sections of the preoptic region of adult female rainbow trout (Oncorhynchus mykiss). Estrogen recep...

journal_title：Neuroendocrinology

authors： Linard B,Anglade I,Corio M,Navas JM,Pakdel F,Saligaut C,Kah O

更新日期：1996-02-01 00:00:00

abstract：:Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...

journal_title：Neuroendocrinology

authors： Simar MR,Saphier D,Goeders NE

更新日期：1996-01-01 00:00:00

abstract：:Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...

journal_title：Neuroendocrinology

authors： González-Parra S,Chowen JA,García-Segura LM,Argente J

更新日期：1996-01-01 00:00:00

abstract：:The neurohypophysial peptide hormone [Arg8]vasopressin (AVP) has well documented pressor effects in the periphery. These are mediated by vasopressin receptors (VPRs) of the V1a subtype, expressed by vascular smooth muscle cells, which induce vascular contraction when activated. AVP also has effects on the vasculature ...

journal_title：Neuroendocrinology

authors： Sermasi E,Howl J,Pyner S,Wheatley M,Coote JH

更新日期：1995-12-01 00:00:00

abstract：:The hypothalamic GnRH pulse generator activity, which was assessed by the characteristic increases in the multiple unit activity (MUA) specifically associated with the pulsatile LH secretion (MUA volleys), was monitored throughout the estrous cycle of the female goat. Blood samples were collected daily for analysis of...

journal_title：Neuroendocrinology

authors： Tanaka T,Ozawa T,Hoshino K,Mori Y

更新日期：1995-12-01 00:00:00

abstract：:Many aspects of reproductive neuroendocrine function and sexual behavior are responsive to both androgens and estrogens, suggesting that receptors for these steroid hormones may reside within single cells in brain regions that control reproductive function. We determined the distribution of estrogen receptor-containin...

journal_title：Neuroendocrinology

authors： Wood RI,Newman SW

更新日期：1995-11-01 00:00:00

abstract：:In this study, radiolabeled recombinant rat interleukin-1 beta (r125I-IL-1 beta) was used to localize and characterize IL-1 beta binding in rat hypothalamus and pituitary gland by quantitative autoradiography. The ability of this ligand to bind to type I IL-1 receptor was first tested on murine lymphoma cells (EL-4). ...

journal_title：Neuroendocrinology

authors： Marquette C,Van Dam AM,Ban E,Lanièce P,Crumeyrolle-Arias M,Fillion G,Berkenbosch F,Haour F

更新日期：1995-10-01 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) or intracarotid (i.a.) administration of amylin (AMY) on growth hormone (GH) release induced by GH-releasing hormone (GHRH) were examined in conscious male rats. Amylin (25 ng-5 micrograms/rat, i.c.v. or 10 micrograms/rat, i.a.) was administered 10 min before GHRH (2 mic...

journal_title：Neuroendocrinology

authors： Netti C,Sibilia V,Pagani F,Lattuada N,Coluzzi M,Pecile A,Guidobono F

更新日期：1995-09-01 00:00:00

abstract：:The present study investigated the effects of short-term exposure to constant light, initiated at the time of ovariectomy, on the ability of estradiol (E2) treatment alone or in conjunction with progesterone (P) to induce afternoon surges of LH and prolactin (PRL). Adult Fischer 344 rats, which had been ovariectomized...

journal_title：Neuroendocrinology

authors： Sterner MR,Cohen IR

更新日期：1995-09-01 00:00:00

abstract：:The possibility was investigated that centrally administered rat prolactin (PRL), i.e., intracerebroventricularly (ICV) or intrathecally (IT), may influence mammary contractility in urethane-anesthetized lactating rats. In addition to the monomer (23 kD PRL), the 16- and 7-kD PRL fragments were also tested and their e...

journal_title：Neuroendocrinology

authors： Morales MT,Mena F

更新日期：1995-08-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:Observations in experimental allergic encephalomyelitis (EAE), a model for multiple sclerosis (MS), have indicated that a low activity of the hypothalamo-pituitary-adrenal (HPA) system is accompanied by a high susceptibility for EAE in rat strains and that elevated corticosteroid levels are necessary for spontaneous r...

journal_title：Neuroendocrinology

authors： Purba JS,Raadsheer FC,Hofman MA,Ravid R,Polman CH,Kamphorst W,Swaab DF

更新日期：1995-07-01 00:00:00

abstract：:Correlations between the specific binding of radiolabelled adrenoligands in frontal cortex and hypothalamus, and plasma testosterone levels were investigated in inbred mouse strains. Binding values were structure and genotype dependent. There were significant negative intrastrain and interstrain correlations between h...

journal_title：Neuroendocrinology

authors： Shishkina GT,Naumenko EV

更新日期：1995-06-01 00:00:00